The chromosomal change usually occurs as a random event during the formation of sperm cells. An error in cell division called nondisjunction can result in sperm cells with an extra copy of the Y chromosome. If one of these atypical reproductive cells contributes to the genetic makeup of a child, the child will have an extra Y chromosome in each of the body's cells.
It occurs as a random event during cell division in early embryonic development. Genetics Home Reference has merged with MedlinePlus. Learn more. The information on this site should not be used as a substitute for professional medical care or advice.
Contact a health care provider if you have questions about your health. From Genetics Home Reference. Description 47,XYY syndrome is characterized by an extra copy of the Y chromosome in each of a male's cells. Many organizations provide educational materials and can help you find doctors who specialize in symptoms related to the syndrome. There are also online communities that offer support as well as practical advice and tips. Here are two we recommend. Unique , supports, informs and networks with anyone affected by a rare chromosome disorder or an autosomal dominant single gene disorder.
By subscribing you agree to the Terms of Use and Privacy Policy. Health Topics. Health Tools. XYY Syndrome. Reviewed: November 10, Medically Reviewed. A diagnosis can be confirmed with prenatal tests such as an amniocentesis or chorionic villus sampling CVS. Treatment Treatment. The signs and symptoms of 47, XYY syndrome can be managed with a variety of therapies.
Occupational therapy may be recommended for infants and young boys who have low muscle tone hypotonia , and speech therapy may be recommended for boys who have speech delay.
Boys with 47, XYY syndrome may be in special education at school, or they may have extra help in some classes. If autism spectrum disorder is present, applied behavioral analysis ABA therapy may be recommended. Prognosis Prognosis. The long-term outlook for people with 47, XYY is typically good. Boys with this syndrome can do well both in school and in building social relationships.
Men with 47, XYY syndrome can also have successful careers and families of their own. Organizations Organizations. Organizations Supporting this Disease. Social Networking Websites. Do you know of an organization? Learn More Learn More. Click on the link above to view this information. This website is maintained by the National Library of Medicine.
The Merck Manuals Online Medical Library provides information on this condition for patients and caregivers.
NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them. Click on the link above to view this information page. In-Depth Information The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers.
This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge. PubMed is a searchable database of medical literature and lists journal articles that discuss 47, XYY syndrome.
Click on the link to view a sample search on this topic. Submit a new question 47,XYY syndrome was present in my first delivery. See answer I have a 4 year old son who was diagnosed with XYY karotype about a year ago. See answer Have a question? References References. Genetics Home Reference. Ross J and Bishop D. Lenroot RK. XYY Syndrome. National Organization for Rare Disorders. Oral, physical, and behavioral aspects of patient with chromosome 47, XYY syndrome.
October-December ; 33 4 Clinical aspects of infertile 47,XYY patients: a retrospective study. Human Fertility. Positive effects of early androgen therapy on the behavioral phenotype of boys with 47,XXY. June ; 2 Do you know of a review article? Share this content:. Close Copy Link. This chromosome arrangement is called 47,XYY. XYY happens as a random event when a sperm is being formed and is not inherited.
The diagnosis is usually made by a blood test that shows an extra Y chromosome in a male. XYY is rarely diagnosed at birth since babies with this condition look like other babies. Chromosome testing may be offered for children with learning delays or autistic behaviors. The sample can be obtained either by a chorionic villus sampling CVS or amniocentesis procedure.
More testing is needed to confirm the diagnosis.
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